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Clear, sourced guides on what Semax is, where it came from, and what the research says.
What is Semax?
Heptapeptide MEHFPGP (Semax's seven-letter amino-acid code), an adrenocorticotropic hormone (ACTH) fragment analog, nasal Rx in Russia.
Origin story
From the “KGB peptide” and “Limitless peptide” nicknames to the Institute of Molecular Genetics record.
How Semax works
Brain-derived neurotrophic factor (BDNF) / its receptor TrkB signals in animals, and the open questions that remain.
Evidence map
Russian clinical contexts and Western replication gaps.
Safety & FAQs
Context only. Quality caveats. Not medical advice.
Semax vs Selank
Related peptides, different aims. Keep them straight.
Regulatory status
Russia Vital & Essential Drugs lists; not U.S. Food and Drug Administration (FDA) / European Medicines Agency (EMA)-approved.
Sources
Footnotes hub. We flag what still needs a citation.